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In China, the burden of chronic obstructive disease (COPD) is high in never-smokers but little is known about its causes in this group. We analysed data on 287 000 female and 30 000 male never-smokers aged 30-79 years from 10 regions in China, who participated in the China Kadoorie Biobank baseline survey (2004-2008). Prevalence of airflow obstruction (AFO) (pre-bronchodilator forced expiratory volume in 1 s (FEV1)/forced vital capacity (FVC) <0.7 and below the lower limit of normal (LLN)) was estimated, by age and region. Cross-sectional associations of AFO (FEV1/FVC <0.7), adjusted for confounding, were examined. AFO prevalence defined as FEV1/FVC <0.7 was 4.0% in females and 5.1% in males (mean ages 51 and 54 years, respectively). AFO prevalence defined as FEV1/FVC

Original publication

DOI

10.1183/09031936.00152413

Type

Journal article

Journal

Eur Respir J

Publication Date

07/2014

Volume

44

Pages

66 - 77

Keywords

Adult, Aged, Air Pollution, Indoor, Asthma, Body Mass Index, China, Cooking, Cross-Sectional Studies, Female, Forced Expiratory Volume, Humans, Male, Middle Aged, Odds Ratio, Prevalence, Pulmonary Disease, Chronic Obstructive, Respiration, Smoking, Spirometry, Surveys and Questionnaires, Vital Capacity